CASE REPORT
The twin reversed arterial perfusion syndrome (TRAP sequence)
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1
Malopolski Institute of Fertility Diagnostics and Treatment – KrakOvi, Krakow, Poland
2
Fertility Disorders Clinic, Medical College, Andrzej Frycz Modrzewski Krakow University, Poland
3
Clinic of Gynaecological Endocrinology at the Jagiellonian University Medical College in Krakow, Poland
4
Artvimed, Krakow, Poland
Submission date: 2025-11-16
Final revision date: 2026-01-04
Acceptance date: 2026-01-07
Publication date: 2026-02-19
Corresponding author
Jakub Wyroba
Małopolski Instytut Diagnostyki i Leczenia Niepłodności KrakOvi
Medicine and Public Health 2025;3(2):15-21
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ABSTRACT
Background:
The twin reversed arterial perfusion syndrome (TRAP sequence) is a rare congenital sequence and a serious complication of monochorionic multiple pregnancies. The frequency of this sequence is estimated at 1:35,000 pregnancies and 1% of monochorionic pregnancies. In this sequence, one fetus is described as a “semi-donor” or “twin-pumping” (autosite), and the second as a twin acardiac (acardiac twin). The cause is considered to be arteriovenous anastomoses in the placenta, which lead to blood transfusion between the twins.
Material and methods:
In this article, we report a case of monochorionic monoamniotic pregnancy resulting from natural fertilization, complicated by TRAP sequence.
Results:
The patient gave birth by cesarean section at 34 weeks’ gestation to a neonate weighing 2350 g, length 43 cm, with an Apgar score of 8/10.
Conclusions:
The outcome of a course of maternity care and possible treatment options in the event of TRAP sequence, as reviewed in the literature, are presented in the article.